The cutaneous synthesis of vitamin D and of its specific receptor (VDR) declines with ageing and with lower exposure to the sun, thus weakening the barrier function of the skin. To address this problem, Silab is launching Vederine, a new vitamin D-like active derived from the chicory root and with a high concentration in oligofructosanes. Vederine activates the vitamin D receptor without the need of sun exposure.

Mimicking the action of vitamin D, Vederine enables mature skin to regain an optimal epidermal barrier. Vederine activates the signal pathways regulated by the VDR, stimulates the molecular network involved in the terminal differentiation of keratinocytes and accelerates the recovery of the barrier function.

In vivo tests on mature skins with a 3% concentration have led to a significant decrease in transepidermal water loss after exposure to sodium lauryl sulphate. The effect appears after 7 days of twice daily applications. Vederine has a healing effect and can be incorporated into all skin care products for mature and insufficiently vitaminated skins.

Silab opens a branch office in South America

To sustain its growth and development strategy, Silab opened its new promoting platform in São Paulo, Brazil, in June 2012.

This entity will be dedicated to the promotion of the company’s natural cosmetic active ingredients and to the management of distributors in place and to be, and so, for the whole South American territory.

Mr. Francisco Santin De Souza, a former manager at Cosmotec, will be in charge of running this new structure.